Search
forLearn
5 / 8 resultslearn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Dutasteride
Heavy duty finasteride that comes with higher risks, but scalp injections seem safe and are gaining popularity
learn Saw Palmetto
a natural and far less effective alternative to Finasteride
learn Azelaic Acid
acid used for antimicrobial, anti-inflammatory and anti-androgenic properties
Research
5 / 1000+ results![Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands](/images/research/201f0f51-82f0-436b-b933-3506dd3c0ea9/small/20516.jpg)
research Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands
The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.
![Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives](/images/research/22ca8539-6e7c-4269-937f-87a4b2b13a2e/small/28160.jpg)
research Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
![Photobiomodulation of human dermal fibroblasts in vitro: decisive role of cell culture conditions and treatment protocols on experimental outcome](/images/research/82ca75a8-c31c-4d7c-9523-868d348d57f1/small/25913.jpg)
research Photobiomodulation of human dermal fibroblasts in vitro: decisive role of cell culture conditions and treatment protocols on experimental outcome
Different lab conditions and light treatment methods change how human skin cells respond to light therapy.
![Androgens and androgen receptor action in skin and hair follicles](/images/research/5cf183ae-90fc-4f0b-b922-b3b64689b16f/small/15994.jpg)
research Androgens and androgen receptor action in skin and hair follicles
Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.
![Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models](/images/research/20ca005c-1115-4511-b25e-bdc6473a6e9d/small/22975.jpg)
research Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.
Community Join
5 / 625 resultscommunity Is this broscience? From More Plates, More Dates
The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.
community Inhibition of 5 alpha-reductase activity in human skin by zinc and azelaic acid????
The post discusses using a topical tincture containing zinc, azelaic acid, and other ingredients to inhibit 5 alpha-reductase activity for treating hair loss. The user plans to try this natural alternative before using finasteride or RU58841.
community Glycine supplementaion is said to strongly upregulate 5-alpha Reductase (5-ar) Activity
Glycine supplementation may increase 5-alpha reductase activity, potentially affecting hair loss. Users discuss its impact on hair fall and its role in the body.
community Theoretically won't this be better than finasteride? Azelaic acid + zinc
The conversation discusses using zinc sulphate and azelaic acid to inhibit 5 alpha-reductase activity, which could potentially treat androgen-related skin conditions like hair loss. Combining these with vitamin B6 could enhance the effect, potentially offering an alternative to finasteride.
community What About Phytosterol Alternatives - Rice Bran Oil - Natural DHT Blockers
The conversation discusses natural DHT blockers like rice bran oil, which may reduce 5α-reductase activity similarly to Minoxidil and Dutasteride. One user argues that finasteride is more reliable and effective than natural alternatives.