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Research

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research The measurement of haloperidol and reduced haloperidol in hair as an index of dosage history.

72 citations , February 1990 in “British Journal of Clinical Pharmacology”

This study found that concentrations of haloperidol and its metabolite in human scalp hair significantly correlated with the daily dose and plasma trough levels in patients taking haloperidol.

Isoallopregnanolone Reduces Tic-Like Behaviors in the D1CT-7 Mouse Model of Tourette Syndrome

research Isoallopregnanolone reduces tic‐like behaviours in the D1 CT ‐7 mouse model of Tourette syndrome

15 citations , June 2019 in “Journal of Neuroendocrinology”

This study found that isoallopregnanolone reduced stress-induced tic-like behaviors and sensorimotor gating deficits in a mouse model of Tourette syndrome, suggesting potential therapeutic properties comparable to existing treatments like haloperidol and finasteride.

research Role of prolactin in regulating the onset of winter fur growth in mink (Mustela vison): A reconsideration

12 citations , September 1999 in “The journal of experimental zoology/Journal of experimental zoology”

This study found that reducing circulating PRL levels is not necessary for the onset of winter hair growth in mink and that adrenal glands do not inhibit this process through DHEA or its metabolite Delta(5)-DIOL.

Trichotillomania: A Review of Impulse-Control Disorder and Treatment Options

research Trichotillomania

3 citations , December 2001 in “Irish Journal of Psychological Medicine”

This review discusses trichotillomania, its diagnosis, prevalence, potential brain abnormalities, and current treatment options, and offers no new clinical findings.

research Inhibition of 17α-hydroxylase/C17,20 lyase reduces gating deficits consequent to dopaminergic activation

19 citations , September 2013 in “Psychoneuroendocrinology”

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

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Community Join

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community Horrible news, Stemson Therapeutics has shut down

193 upvotes 1 year ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community Reduced libido + almost no morning erections after 1.5 years of topical finasteride + minoxidil — should I stop finasteride?

72 upvotes 1 week ago

A user experienced reduced libido and fewer morning erections after 1.5 years of using topical finasteride and minoxidil for hair loss. They are considering stopping finasteride due to these side effects and are seeking advice on whether their libido will return to normal and if minoxidil alone will maintain their hair density.

community Reduced excessive hair shedding

193 upvotes 2 months ago

Scalp microneedling with Exohealer significantly reduced hair shedding for the user. The treatment was done at Seoul Forena Clinic.

community further reduce DHT in the scalp

in Finasteride/Dutasteride 428 upvotes 6 months ago

The conversation discusses methods to further reduce DHT in the scalp for hair loss treatment, with users suggesting various approaches like using dutasteride, minoxidil, tretinoin, and natural supplements like pumpkin seed oil. Some users also mention using topical applications and scalp massages to enhance the effectiveness of these treatments.

community I reduced my serum DHT by 60% without Fin/Dut but not seeing any real stabilization or growth

in Update 2 upvotes 1 year ago

The user reduced serum DHT by 60% using Advanced Trichology's natural DHT blocker but saw no improvement in hair loss. They are considering switching to finasteride due to its proven effectiveness in inhibiting scalp DHT.

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Learn

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learn Cetirizine

How does cetirizine reduce inflammation linked to hair loss? Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.

learn Folic acid

Can folic acid help reduce hair loss in men and women, and how should it be taken? Correcting a confirmed folate deficiency is reasonable, but no published trial shows folic acid supplementation reduces hair loss on its own; the evidence is a few small observational studies and reviews that call for proper trials.

learn Ginkgo biloba

Can ginkgo biloba reduce scalp inflammation that contributes to hair loss? Ginkgo biloba may help reduce scalp inflammation, potentially benefiting hair loss.

learn Hyaluronic Acid

Can hyaluronic acid help reduce scalp irritation from medical treatments like minoxidil? Yes, hyaluronic acid can help reduce scalp irritation from minoxidil.

learn Niacinamide

Can Niacinamide help reduce scalp irritation or dandruff? Niacinamide may help reduce scalp irritation and dandruff by improving skin barrier function.

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