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research Reductive Stress Selectively Disrupts Collagen Homeostasis and Modifies Growth Factor-independent Signaling Through the MAPK/Akt Pathway in Human Dermal Fibroblasts

9 citations, March 2019 in “Molecular & cellular proteomics”

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

research Oxidative Stress: Insights into the Pathogenesis and Treatment of Alopecia

January 2023 in “Journal of Ravishankar University”

Hair loss can be caused by stress, aging, and harmful substances that create an imbalance in the body's natural processes.

research Antioxidants in Dermatology

86 citations, June 2017 in “Anais Brasileiros de Dermatologia”

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

research The Regulatory Mechanisms of Mitophagy and Oxidative Stress in Androgenetic Alopecia

May 2025 in “Cellular Signalling”

Oxidative stress and mitophagy play key roles in hair loss, suggesting potential treatment targets.

research Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond?

30 citations, July 2017 in “BioEssays”

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

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Community Join

5 / 23 results

community Bile Acid-Mediated DHT Dysregulation Hypothesis

in Research/Science 13 upvotes 6 months ago

Elevated bile acids can inhibit the enzyme AKR1C2, leading to increased DHT levels, which may accelerate hair loss in those predisposed to androgenetic alopecia. Treatments mentioned include topical minoxidil and finasteride.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 479 upvotes 10 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community Update about Hair Follicle Glucose Metabolism: New Clinical Data Collection with Ex-President Of American Board Of Hair Restoration Surgery.

in Research/Science 39 upvotes 10 months ago

David Barreto shared that a London-based research group is conducting a 12-month trial for a new nutraceutical treatment for pattern hair loss, designed with Dr. Carlos Puig. The trial aims to provide robust data, with results expected in 1-2 years, potentially representing a significant advancement since finasteride’s introduction in 1997.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 40 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Month 2.5 redo. Topical fin/min microneedling once a week.

in Progress Pictures 18 upvotes 1 year ago

A user who initially had positive results with oral finasteride, topical minoxidil, and microneedling for hair loss, but experienced side effects like fog and depression. After stopping and losing progress, they restarted with topical treatments and microneedling, reporting good results and no side effects.

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