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Reconstructed Human Skin Shows Epidermal Invagination Towards Integrated Neopapillae Indicating Early Hair Follicle Formation In Vitro

research Reconstructed Human Skin Shows Epidermal Invagination Towards Integrated Neopapillae Indicating Early Hair Follicle Formation In Vitro

29 citations, April 2020 in “Journal of Tissue Engineering and Regenerative Medicine”

The experiment showed that human skin grown in the lab started to form early hair structures when special cell clusters were added.

Glutathione Distribution by Quantitative MALDI Imaging in Reconstructed Human Skin Upon Activation of GSH Biosynthesis by Nrf2 Pathway Activator

research Glutathione Distribution by Quantitative MALDI Imaging in Reconstructed Human Skin Upon Activation of GSH Biosynthesis by Nrf2 Pathway Activator

April 2018 in “Journal of Investigative Dermatology”

Resveratrol activates the Nrf2 pathway in human skin, significantly increasing the production and distribution of the antioxidant glutathione.

research Comparison of Glutathione S-Transferase and Cytochrome P-450 IA1 Activities in Cultured Keratinocytes and Reconstructed Epidermal Models

42 citations, January 2002 in “Skin Pharmacology and Physiology”

Reconstructed skin models are useful for studying how skin processes certain chemicals.

research Characterization of Xenobiotic Metabolizing Enzymes of a Reconstructed Human Epidermal Model from Adult Hair Follicles

September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology”

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

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community Redensyl (The Ordinary Serum)

in Treatment 20 upvotes 4 years ago

Redensyl, a hair loss treatment that has been claimed to be 80% more effective than minoxidil, but users have not experienced any results from using it.

community Discussion on Finasteride and life.

in Chat 164 upvotes 2 months ago

Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

community 11 months on fin + min. Thoughts?

in Progress Pictures 916 upvotes 4 months ago

A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

community Before hair transplant and after 19 months update, no finasteride no minoxidil only some vitamins

in Update 294 upvotes 3 years ago

A user shared their positive hair transplant results after 19 months without using finasteride or minoxidil, only vitamins. Some responses suggest concern over future hair loss without prevention treatments, while others congratulate or express jealousy.

community Dutasteride might be better for your hairline. Some people have more type 1 5AR activity in their scalp than others.

in Finasteride/Dutasteride 52 upvotes 1 year ago

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

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