1 citations
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January 2005 in “Experimental Dermatology” This study found that antisense oligonucleotides successfully reduced androgen receptor expression in human keratinocytes and reconstituted human epidermis, suggesting potential for developing topical treatments.
103 citations
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April 2010 in “Journal of Investigative Dermatology” This study reports that human eccrine sweat gland cells are capable of forming a stratified epidermis, suggesting they may serve as an additional source of keratinocytes for skin repair.
27 citations
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June 2015 in “Journal of photochemistry and photobiology. B, Biology” This study reported that sunscreen with SPF50+ provides a high level of DNA protection against UV-induced damage in a reconstituted human epidermis model, comparable to that in skin explants.
6 citations
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January 2018 in “Advances in experimental medicine and biology” This research reports that Muse cells from human skin can be differentiated into melanocytes, fibroblasts, and keratinocytes, enabling the creation of 3D reconstituted skin, potentially advancing skin reconstruction therapies.
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers found that SPF50+ sunscreens provided the highest DNA protection against solar-simulated radiation in a reconstituted human epidermis model, with formulation type not affecting efficacy for a given SPF.
