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research Where Have the Periods Gone? The Evaluation and Management of Functional Hypothalamic Amenorrhea

18 citations, January 2020 in “Journal of Clinical Research in Pediatric Endocrinology”

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

research Hair Cycle Control by Leptin as a New Anagen Inducer

41 citations, November 2013 in “Experimental Dermatology”

Leptin, a hormone, is important for starting hair growth.

research Rabson-Mendenhall Syndrome: Two Case Reports and a Brief Review of the Literature

18 citations, February 2010 in “Odontology”

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

research Anorexia Nervosa and Bulimia Nervosa: Analysis of Prevalence, Mortality, Outcomes, and Endocrine Changes

1 citations, January 2009 in “Elsevier eBooks”

Anorexia Nervosa and Bulimia Nervosa are complex eating disorders with increasing incidence among young females, significant morbidity, and varying mortality rates, requiring more research for better treatment.

research A Clinical Approach to Severe Insulin Resistance

32 citations, January 2007 in “KARGER eBooks”

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

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community SCUBE3 is going to save us!!! This is the news we've all been waiting for...

in Research/Science 89 upvotes 2 years ago

User discusses potential hair loss treatment SCUBE3 and shares mixed opinions on its effectiveness. One user reports positive results after applying SCUBE3 following microneedling.

community FCE 28260: A Forgotten 5α-Reductase Inhibitor

in Research 330 upvotes 3 months ago

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community The theory that explains everything. Please help me make this big!

in Research/Science 2453 upvotes 3 years ago

The post and conversation are about the role of the enzyme 3alpha-hydroxysteroid reductase in hair loss and the potential of compounds like procyanidin B2 and sulforaphane to boost its activity for hair regrowth. Further research is needed to develop effective treatments based on this theory.

community Tropoelastin injections + verteporfin?

in Research/Science 12 upvotes 1 year ago

The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

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