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research Human Hair Follicles Can Taste: Stimulation of the Bitter Taste Receptor TAS2R4 Inhibits Hair Growth Ex Vivo by Up-Regulating TGF-β2

November 2022 in “Journal of Investigative Dermatology”

Activating a bitter taste receptor in hair follicles can stop hair growth by increasing a specific growth factor.

Histologic Progression of Acne Inversa/Hidradenitis Suppurativa: Implications for Future Investigations and Therapeutic Intervention

research Histologic Progression of Acne Inversa/Hidradenitis Suppurativa: Implications for Future Investigations and Therapeutic Intervention

19 citations, January 2021 in “Experimental dermatology”

Acne inversa is an epithelial-driven disease where inflammation is caused by cyst rupture, and treatments should focus on preventing tendril growth for better results.

research The Human Hair Follicle, A Bistable Organ?

45 citations, January 2012 in “Experimental Dermatology”

Human hair follicles switch between active and resting phases unpredictably.

research From Basal Cell Carcinoma Morphogenesis to Alopecia Induced by Hedgehog Inhibitors: Connecting the Dots

17 citations, June 2017 in “British Journal of Dermatology”

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

research Pegylated Liposomal Doxorubicin: Metamorphosis of an Old Drug into a New Form of Chemotherapy

522 citations, January 2001 in “Cancer investigation”

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

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Community Join

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community Started my treatment today. Wish me luck guys.

in Finasteride 8 upvotes 6 years ago

A 43-year-old man started treatment for hair loss with finasteride, minoxidil, Qilib rebalance, and Trigain Caffeine shampoo, and is taking vitamin D supplements. He hopes to share positive results after a few months.

community 2 year fin/min progress (age 27-29)

in Progress Pictures 302 upvotes 1 year ago

A user's two-year progress using 1mg of oral finasteride daily and twice daily application of 5% minoxidil solution for hair loss. The user experienced temporary side effects but is pleased with the results, and another user warns about the importance of consistent use for maintaining results.

community Topical Anti-Androgen users. What are y’all using currently? And what do you believe has the best chance of being approved? Or best results?

in Technology 13 upvotes 1 month ago

RU58841 is considered effective by some users, but finasteride and minoxidil are commonly used with varying dosages to manage side effects. Users report different experiences with treatments like pyrilutamide, fluridil, and RU58841, with some seeing results and others not.

community Sustaining minoxidil dependent hairs?

in Research/Science 9 upvotes 6 months ago

Minoxidil-dependent hairs fall out if minoxidil is stopped. New treatments like GT20029, FOL055, or TDM105795 might help sustain these hairs.

community Thoughts on this Article: Post-Finasteride and Neurological Effects

in Finasteride/Dutasteride 14 upvotes 8 months ago

The conversation discusses the effects of finasteride on hair loss and its potential neurological and sexual side effects. Users share personal experiences, with some reporting positive outcomes and others expressing concerns about cognitive function.

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