In this case report, a 74-year-old woman with progressive alopecia unresponsive to minoxidil was diagnosed with Graham-Little-Piccardi-Lassueur Syndrome, illustrating the value of interdisciplinary collaboration in primary care for accurate diagnosis and improved patient outcomes.
76 citations
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January 1998 in “Mammalian Genome” 
127 citations
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July 2002 in “EMBO journal” This study found that RXRα/RARγ heterodimers are necessary for retinoic acid-induced keratinocyte proliferation in the skin, while normal epidermal maintenance does not require RAR-mediated signaling.
51 citations
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March 2014 in “Nature Communications” This study suggests that activating retinoic acid signalling can inhibit Wnt signalling and induce regression in certain skin tumors, providing potential therapeutic strategies for tumor regression.
47 citations
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June 2019 in “Nature Communications” This study found that self-noncoding dsRNA activates TLR3 to stimulate intrinsic retinoic acid synthesis, promoting new hair follicle formation in wounded mice and showing similar gene expression changes in humans treated with rejuvenation lasers.