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Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

research Data from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

March 2023

This study suggests that targeting the activation of transit-amplifying cell-derived progenitor cells may help prevent hair loss from chemotherapy and radiotherapy by promoting hair follicle regeneration.

research Reduction of Radiation-Induced Hair Loss by Topical Application of Radioprotectors

1 citations , January 1994 in “Drug Development and Industrial Pharmacy”

This study suggests that certain combinations of topical radioprotectors and vehicles can reduce radiation-induced hair loss in mice, with effectiveness varying by radiation dose and vehicle type.

research Supplementary Figures, Tables and Legends from Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

March 2023

Results are not reported in this study, which investigated the effects of radiation on hair follicles and evaluated various cellular responses and signaling pathways, particularly focusing on WNT signaling and the impact of Wnt3a treatment.

research Mobilizing Transit-Amplifying Cell-Derived Ectopic Progenitors Prevents Hair Loss from Chemotherapy or Radiation Therapy

38 citations , September 2017 in “Cancer Research”

This study reports that hair follicles can mobilize ectopic progenitors for regeneration to repair damage from ionizing radiation. Augmenting WNT signaling enhanced this regenerative process and prevented radiation- and chemotherapy-induced hair loss, highlighting a potential approach to manage alopecia during cancer treatment.

Valproic Acid Reduces Hair Loss and Improves Survival in Patients Receiving Temozolomide-Based Radiation Therapy for High-Grade Glioma

research Valproic acid reduces hair loss and improves survival in patients receiving temozolomide-based radiation therapy for high-grade glioma

26 citations , November 2016 in “European Journal of Clinical Pharmacology”

This study found that using valproic acid during radiotherapy for glioma was associated with delayed hair loss and improved survival outcomes.

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Community Join

5 / 49 results

community Hair Loss Drugs Ranked in Order of Efficacy

in Research/Science 67 upvotes 2 years ago

Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

community Before and after female hair loss

72 upvotes 1 month ago

OP has been using spironolactone and minoxidil for 3 years with slow hair growth results, possibly affected by vaping. Users suggest adding microneedling, hair serum, dietary changes, and checking spironolactone dosage for better results.

community Most Underrated Hack for Hair Loss is Water

in Chat 68 upvotes 8 months ago

Filtered shower heads may improve scalp and hair health but do not affect male pattern baldness (MPB). Genetics and factors like DHT and scalp tension are more significant in hair loss.

community I think I’ve finally found the reason for my hair loss

in Chat 98 upvotes 1 year ago

The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

community Sunlight: Does it Stimulate Hair Growth or Hair Loss?

in Research/Science 64 upvotes 2 years ago

The conversation discusses whether sunlight exposure affects hair growth or loss, with mixed anecdotes and theories but no clear consensus. Some suggest moderate sunlight can benefit hair by providing vitamin D, while others doubt its effectiveness compared to treatments like Minoxidil or finasteride.

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Learn

7 / 801 results

learn Sulforaphane

compound from cruciferous vegetables has some mild effects on DHT

learn Alfatradiol

Alfatradiol: Can it help if my hair loss is linked to DHT? The one randomised trial of topical alfatradiol — in 103 women — found hair thickness and density essentially unchanged after six months, while minoxidil improved both; its authors credited alfatradiol with slowing hair loss rather than regrowing hair. Laboratory work supports a local effect on follicular DHT, but no controlled trial in men appears to have been published.
Alfatradiol: What does a form of estrogen have to do with hair loss in men? Alfatradiol (17α-estradiol) is a prescription topical hormone, licensed for androgenetic alopecia in Germany but not FDA-approved. The controlled trial evidence is in women, where it produced stabilisation rather than regrowth and was outperformed by minoxidil; no comparable placebo-controlled trial in men appears to have been published.

learn Alopecia Areata

autoimmune disorder causing patchy hair loss

learn RU58841

Will I lose my hair if I stop using RU58841? (Spoiler: I might.) There is no published human trial of stopping RU58841; community members commonly report shedding within weeks to months, and androgen biology suggests miniaturization would resume once the topical anti-androgen is withdrawn.

learn Hair Transplant

Hair transplantation moves DHT-resistant follicles from a donor area (back and sides of the scalp) into thinning or bald areas. The transplanted hair is generally permanent, though surrounding native hair can keep thinning.

Can a hair transplant cause cancer? Hair transplants do not cause cancer according to most providers.

learn Scalp Micropigmentation

Does scalp micropigmentation cause hair loss? Scalp micropigmentation does not cause hair loss and is a cosmetic treatment.

learn Low Level Laser Therapy

laser therapy for anti-inflammatory and likely insignificant hair regrowth effects

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