236 citations
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April 2015 in “Cell” This study found that patterned hair plucking in mice triggers a collective regeneration response in nearby unplucked hair follicles via a quorum sensing mechanism involving immune signaling.
44 citations
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March 2020 in “Antibiotics” The researchers reported that carnosic acid and carnosol, extracts from rosemary leaves, specifically inhibit S. aureus virulence expression, suggesting potential topical treatments for atopic dermatitis flares.
12 citations
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August 2016 in “Current opinion in genetics & development” In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.
1 citations
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October 2025 in “Journal of Clinical Investigation” This study found that Staphylococcus aureus delays wound healing by utilizing quorum sensing to impair lipid metabolism in keratinocytes, an effect not observed with commensal Staphylococcus, highlighting the impact of agr-dependent virulence factors in this process.
May 2025 in “Zagazig Journal of Pharmaceutical Sciences/Zagazig Journal of Pharmaceutical Science” In laboratory settings, this study found that finasteride repurposed as a quorum sensing inhibitor significantly reduced virulence factors of Pseudomonas aeruginosa, including biofilm formation by 45% and pyocyanin production by 49%, suggesting potential for treating infections.