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Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production

research Synthesis and Biological Evaluation of Amino-Pyridines as Androgen Receptor Antagonists for Stimulating Hair Growth and Reducing Sebum Production

17 citations , August 2007 in “Bioorganic & Medicinal Chemistry Letters”

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

research The Rotterdam Study: 2018 Update on Objectives, Design, and Main Results

359 citations , September 2017 in “European Journal of Epidemiology”

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

research 5α-Reductase Activity in the Prostate

237 citations , December 2001 in “Urology”

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

research Steroid Sulfatase Inhibitors: Therapeutic Applications and Development

25 citations , May 2003 in “Expert Opinion on Therapeutic Patents”

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

research Androgen Receptor Modulators: A Review of Recent Patents and Reports (2012-2018)

23 citations , May 2019 in “Expert Opinion on Therapeutic Patents”

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

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Community Join

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community Kintor long term safety phase 3

in Research/Science 64 upvotes 6 months ago

Kintor's phase III trial for pyri (KX-826) showed promising safety and efficacy results, with no drug-related sexual dysfunction reported. Users discussed their experiences with pyri, Minoxidil, Dutasteride, and concerns about the validity of the study results.

community Solo use of Pyrilutamide: UPDATE

in Update 45 upvotes 2 years ago

A user who has been using Pyrilutamide for 19 days, experiencing some hair thickening in the right temple and crown area but also having ball ache after microneedling; other users offer advice, caution and skepticism as to whether results can be seen in such a short time.

community My Pyrilutamide Experience Photos

in Update 602 upvotes 2 years ago

A user's experience with Pyrilutamide, a topical treatment for hair loss that they used in combination with other treatments such as Minoxidil and Finasteride. The user experienced impressive results in a short amount of time.

community Starting pyrilutamide. Currently have a 2 month supply. I will actually log my results here unlike the others

in Treatment 112 upvotes 2 years ago

Transitioning from finasteride to Pyrilutamide as a treatment for hair loss, and the potential risks associated with taking such a drug. People have discussed the need to wait at least 6 months in order to assess results, and are willing to risk their health trying this new medication.

community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

in Research/Science 87 upvotes 3 years ago

A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

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