8 citations
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January 2022 in “BMC Biology” This study found that the gene SRD5A1, associated with methylation changes due to early-life environment, may play a role in altering reproductive phenotypes in women by delaying pubertal onset and decreasing ovarian reserve.
284 citations
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February 2008 in “Pediatrics” This review discusses the potential impact of endocrine-disrupting chemicals and body size on pubertal onset and progression, highlighting critical gaps and priorities for future research without presenting new clinical results.
January 2026 in “Reproductive Toxicology” In this study, daughters of mothers who consumed 8 or more cups of coffee per day during pregnancy experienced pubertal development about 2 months earlier than daughters of mothers who did not consume coffee, whereas no such differences were observed among sons.
2 citations
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January 1988 in “Deep Blue (University of Michigan)” This study found that early adolescent girls who perceive themselves as undergoing pubertal changes report more intense and variable moods, with hormone activity and perceived pubertal status independently predicting mood fluctuations.
1 citations
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May 2023 in “Fertility and sterility” In this cohort study of young Danish men, self-reported older age at voice break was linked to certain reproductive hormone changes that suggest reduced male fecundity, but associations with semen characteristics and testicular volume were not statistically significant.