research The anxiolytic-like effects of estazolam on a PTSD animal model
This study found that estazolam improved PTSD-like behavior deficits in an animal model, which was linked to increased allopregnanolone levels in specific brain regions.
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research Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD
This study suggests that cerebrospinal fluid levels of the neurosteroids allopregnanolone and pregnanolone correlate negatively with PTSD and negative mood symptoms, with potential sex-specific differences in synthesis enzyme blocks.
research Long-term complications of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN): the spectrum of chronic problems in patients who survive an episode of SJS/TEN necessitates multidisciplinary follow-up
This review discusses the range of long-term complications, including mucocutaneous, ocular, and psychological sequelae, for survivors of Stevens–Johnson syndrome and toxic epidermal necrolysis, but reports no new clinical results.
research Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
This study found that augmenting or reducing allopregnanolone activity in the BNST affected contextual fear expression in rats, suggesting sex differences in anxiety may be linked to neuroactive steroid regulation.
research Dermatological symptoms and sexual abuse: a review and case reports
This article discusses the diverse dermatological symptoms associated with sexual abuse, highlighting the challenges in establishing causal links and the potential long-term psychosomatic manifestations, without reporting new research results.
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