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Keloids may be influenced by stress and psychological factors.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Men with alopecia areata tend to have larger limb and trunk circumferences than healthy men.

Women with keloid scars often have acne and hair loss, especially those with "true" keloids, indicating a possible hormonal imbalance.