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GlossaryPlatelet-Rich Plasma (PRS)

concentration of platelets from one's own blood to promote healing

Platelet-Rich Plasma (PRP) is a concentration of platelets derived from a small sample of the patient's own blood. These platelets are rich in growth factors that can promote healing and tissue regeneration. PRP is commonly used in medical treatments, including hair restoration for conditions like alopecia, where it is injected into the scalp to stimulate hair growth.

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research Distinct Developmental Functions of Prostasin (CAP1/PRSS8) Zymogen and Activated Prostasin

28 citations, December 2015 in “Journal of biological chemistry/The Journal of biological chemistry”

Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.

research The CAP1/Prss8 Catalytic Triad Is Not Involved in PAR2 Activation and Protease Nexin-1 (PN-1) Inhibition

14 citations, August 2014 in “The FASEB Journal”

CAP1/Prss8 does not activate PAR2 or inhibit PN-1.

research PSSD, PFS, PRSD: A Perspective for Aetiology and Treatment

April 2023

The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.

research A Direct Link Between Prss53, Hair Curvature, and Skeletal Dysplasia

February 2019 in “bioRxiv (Cold Spring Harbor Laboratory)”

The gene Prss53 affects hair shape and bone development in rabbits.

research Diagnostic Criteria for Enduring Sexual Dysfunction After Treatment With Antidepressants, Finasteride, and Isotretinoin

8 citations, October 2021 in “The international journal of risk and safety in medicine”

The document sets criteria for diagnosing long-term sexual dysfunctions caused by certain medications.

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community Latest verteporfin update (9/11/2022)

in Research/Science 15 upvotes 2 years ago

Research and science related to a minor improvement in hair growth caused by the use of verteporfin, as well as potential treatments such as Minoxidil, Finasteride, and RU58841.

community Progress so far after a little over a year (23M)

in Progress Pictures 2741 upvotes 5 months ago

A 23-year-old shared his hair regrowth progress after using Minoxidil, finasteride, Dutasteride, and RU58841 for over a year. The post received supportive comments, with others sharing their own experiences and complimenting his transformation.

community Creatine's effect on Hair Loss and DHT

in Research/Science 100 upvotes 8 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community Fuck it. Everyone’s doing this shit and I live for giving people hope they didn’t have yesterday. Minoxidil + Finasteride for one year. (September 16,2021 – September 21, 2022). And I will keep going until I die. 🔥🔥🚀🚀 let me know what you think .

in Treatment 2 years ago

This user has experienced hair loss, and treated it with a combination of finasteride and minoxidil for one year. They have reported slight heart palpitations and headaches, which diminished after the third month of treatment.

community Kintor Phase 2 Results released KX-826 (pyrilutamide)

in Research/Science 449 upvotes 2 years ago

Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

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