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Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

research Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

40 citations, March 2022 in “Small”

Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.

Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies

research Generating Detailed Intercellular Communication Patterns in Psoriasis at the Single-Cell Level Using Social Networking, Pattern Recognition, and Manifold Learning Methods to Optimize Treatment Strategies

January 2024 in “Aging”

New insights into cell communication in psoriasis suggest innovative drug treatments.

research Embryonic-Like Regenerative Phenomenon: Wound-Induced Hair Follicle Neogenesis

10 citations, September 2018 in “Regenerative Medicine”

New hair can grow from large wounds in mice, but less so as they age, involving reprogramming of skin cells and specific molecular pathways.

research Multimodal Molecular Analysis Reveals Divergent Trajectories of Wound Regeneration Versus Fibrosis

July 2021 in “Plastic and reconstructive surgery. Global open”

Verteporfin treatment in mice led to complete skin healing without scarring.

research Generation of VEGF Knock-In Cashmere Goat via the CRISPR/Cas9 System

12 citations, January 2021 in “International Journal of Biological Sciences”

Scientists successfully edited a goat's genes to grow more and longer cashmere hair.

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community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 month ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community 22 yr asian male 2 year fin results

in Progress Pictures 135 upvotes 1 year ago

The user "Top_Replacement_7777" shared their positive results with finasteride for hair loss. They asked about maintaining their hair with finasteride and the impact of vaping on hair growth. Another user reassured them that vaping wouldn't affect their progress.

community Should I just switch to oral minoxidil + where do you get cheap oral minoxidil in the United States?

in Minoxidil 19 upvotes 1 month ago

Switching from topical to oral minoxidil due to scalp irritation and unsatisfactory results, while also seeking cheaper options in the U.S. Oral minoxidil is generally favored for its effectiveness and fewer application downsides, with CostPlusDrugs and GoodRx offering affordable prices.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 3 months ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community Eliminating scalp itch leads to regrowth (and my RU58841 progress)

in Research/Science 61 upvotes 1 year ago

User experienced hair regrowth after eliminating scalp itch with RU58841. Others discussed itch and hair loss connection, and effectiveness of combining RU58841 with 5AR inhibitors.

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