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research Omics for Precious Rare Biosamples: Characterization of Ancient Human Hair by a Proteomic Approach

7 citations , June 2017 in “Omics”

This study developed a new proteomic method to identify and assess ancient hair proteins using only small amounts of sample, providing insights into hair protein alteration processes over time.

research An in silico approach to the identification of potential proteomic and genomic diagnostic biomarkers for primary cicatricial alopecia

October 2021 in “Experimental Dermatology”

This study explores the use of in silico methods to identify potential diagnostic biomarkers for primary cicatricial alopecia, revealing significant interactions among genes and proteins related to disease pathogenesis.

research Discovery of genes and proteins possibly regulating mean wool fibre diameter using cDNA microarray and proteomic approaches

6 citations , May 2020 in “Scientific reports”

In this study, microarray and proteomic analyses indicated that genes involved in immune response, receptor binding, and growth factor activity might influence wool fibre diameter in sheep.

research Investigations into the roles of potassium channels in hair growth : studies confirming the presence of several ATP-sensitive potassium (K+ATP) channels in hair follicles and exploring their mechanism of action using molecular biological, cell culture, organ culture and proteomic approaches

November 2010 in “Bradford Scholars (University of Bradford)”

In this study, the authors reported that NNC55-9216, a selective SUR1 KATP channel opener, stimulated hair follicle growth in culture and enhanced the effects of minoxidil, suggesting a new potential treatment for hair loss.

research Identification of human hair follicle antigens targeted in the presumptive autoimmune hair follicle disorder alopecia areata and their potential functional relevance in vitro : methods development for isolation and identification of alopecia areata-relevant human hair follicle antigens using a proteomics approach and their functional assessment using an ex vivo hair follicle organ culture model

January 2008 in “Bradford Scholars (University of Bradford)”

This study supports that an antibody response against anagen-specific hair follicle antigens, including trichohyalin and keratin 16, may play a role in alopecia areata.

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community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 2 years ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community Hair Loss Inflammation Prevention Stack

48 upvotes 1 year ago

The conversation discusses a hair loss and scalp care routine involving ciclopirox shampoo, benzoyl peroxide, clindamycin gel, clobetasol propionate, and calcipotriol to manage seborrheic dermatitis, folliculitis, and inflammation. It also touches on the role of diet and other treatments like oral minoxidil and pioglitazone for scalp health.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community I had claude create a protocol only using fda approved drugs.

4 upvotes 8 months ago

A new hair loss protocol using FDA-approved topical treatments targets eight pathways, potentially improving results by 60-75% compared to the standard 40-50% from oral minoxidil and finasteride. The protocol includes minoxidil, finasteride, tacrolimus, cetirizine, bimatoprost, lithium gluconate, losartan, melatonin, NAC, caffeine, and tretinoin, with a monthly cost of $35-50 in Mexico and $80-150 in the US.

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