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GlossaryProteomics (Proteome Analysis)

large-scale study of proteins in biological systems

Proteomics is the large-scale study of proteins, which are vital parts of living organisms and perform a variety of functions within cells. It involves identifying and quantifying proteins, understanding their structures and functions, and how they interact within a biological system. This field is crucial for understanding diseases, including those affecting hair and skin, such as alopecia, by revealing changes in protein expression and function.

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research Proteome Analysis of Human Hair Shaft

122 citations , January 2006 in “Molecular & Cellular Proteomics”

Human hair contains many proteins, with some being highly abundant and modified.

research Studies on the Proteome of Human Hair: Identification of Histones and Deamidated Keratins

54 citations , January 2018 in “Scientific reports”

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

research Proteome Analysis of Human Sebaceous Follicle Infundibula Extracted from Healthy and Acne-Affected Skin

62 citations , September 2014 in “PLoS ONE”

Acne-affected skin has more inflammation-related proteins and bacteria than healthy skin.

research Profiling of Hair Proteome Revealed Individual Demographics

1 citations , July 2023 in “Forensic science international. Genetics”

Hair protein analysis might help identify a person's ethnicity, sex, and age in forensics.

research Proteomic Characterization of Damaged Single Hairs Recovered After an Explosion for Protein-Based Human Identification

10 citations , May 2020 in “Journal of proteome research”

Explosions don't stop hair proteins from being used to identify people.

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community Kintor has announced the results for their human Phase I trials of GT20029

in Research/Science 254 upvotes 3 years ago

The conversation discusses the potential of a new hair loss treatment, GT20029, which may prevent hair loss by destroying androgen receptors on the scalp. Users express hope for the treatment's success and speculate on its usage routine, effectiveness, and possible side effects.

community Fin isn’t working anymore after 3 years, afraid to switch to dut?

in Finasteride/Dutasteride 27 upvotes 1 year ago

Finasteride stopped working for a user after 3 years, and they are considering switching to dutasteride. Other users suggest trying dutasteride, with some sharing positive experiences and additional treatments like minoxidil and RU58841.

community Should I just switch to oral minoxidil + where do you get cheap oral minoxidil in the United States?

in Minoxidil 19 upvotes 1 year ago

Switching from topical to oral minoxidil due to scalp irritation and unsatisfactory results, while also seeking cheaper options in the U.S. Oral minoxidil is generally favored for its effectiveness and fewer application downsides, with CostPlusDrugs and GoodRx offering affordable prices.