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research Isolation and Characterization of Recombinant Murine Wnt3a
Scientists successfully purified a protein called Wnt3a, which is involved in processes like hair growth, but the overall yield was low, suggesting more work is needed to improve this.
research Effect of Heat Treatment on Human Hair Keratin Film
The study investigated the effects of heat treatment on human hair keratin films and hair samples, focusing on color change, morphology, protein solubility, and oxidative proteins. It was found that keratin films changed color from opaque white to yellow/light brown at temperatures above 170°C, with little morphological change observed even at 200°C. Protein solubility decreased with increased heating time and temperature, showing a linear relationship between solubilized proteins and temperatures from 110 to 160°C. The keratin films exhibited more pronounced changes compared to hair samples, with increased carbonylated proteins at 120–180°C, suggesting that heat promotes protein oxidation and the formation of a "Stable Structure." The study concluded that keratin films could be used to quantitatively evaluate hair thermal damage.
research A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study
research Keratin Function and Regulation in Tissue Homeostasis and Pathogenesis
Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.
research Human Hair Keratin Hydrogel: Fabrication, Characterization, and Application
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
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5 / 720 resultscommunity Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?
Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.
community P-1075: a BETTER version of Minoxidil
P-1075 is a more potent hair growth agent than Minoxidil, but it poses significant heart risks, making it unsafe for use. Despite promising results in macaques, concerns about its cardiotoxicity in rats have halted its development.
community I just made 60x of 5mg minoxidil sugar cubes
A user created oral minoxidil sugar cubes due to lack of prescription access, leading to a humorous discussion about unconventional and potentially unsafe methods of using minoxidil. The conversation highlights the lengths people go to for hair growth.
community This serum outperformed Minoxidil in a recent study. Please debunk
A topical solution called "Multi-Peptide Serum for Hair Density" by The Ordinary Company, which contains several ingredients that are used in alternatives to Minoxidil and was found to have better results than 5% Minoxidil in a study. People who have tried it shared their experiences with the serum as well.
community UPDATE: The theory that explains everything. Please help me make this big!
Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.