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Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation

research Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and MiRNAs, and Sustained Release Formulation

40 citations , March 2022 in “Small”

In an animal model, this study found that PEG hydrogels delivering M2 macrophage-derived exosomes effectively promoted M1 to M2 macrophage transition and enhanced wound healing.

research Unique amino acid signatures that are evolutionarily conserved distinguish simple-type, epidermal and hair keratins

76 citations , December 2011 in “Journal of Cell Science”

This study found that keratins have evolutionarily conserved and domain-selectively enriched amino acids, which likely reflect their unique structural roles, with distinct patterns observed among epidermal, hair, and simple-type epithelial keratins.

research Type 1 interferon signature in the scalp lesions of alopecia areata

52 citations , March 2010 in “British Journal of Dermatology”

This study demonstrated the expression of type 1 interferon-related proteins in inflammatory lesions of alopecia areata, showing a distinct distribution pattern compared to cicatricial alopecia.

research Potential use of human hair shaft keratin peptide signatures to distinguish gender and ethnicity

22 citations , January 2020 in “PeerJ”

This study suggests that keratin peptide signatures in human hair shafts could potentially be used to distinguish gender and ethnicity, though further research on a larger scale is needed.

research Resequencing Analyses Revealed Genetic Diversity and Selection Signatures during Rabbit Breeding and Improvement

March 2024 in “Genes”

This study used whole-genome resequencing to analyze genetic diversity and selection in 17 rabbit breeds, identifying genes linked to traits like coat color and body size, which could inform breeding and conservation efforts.

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community PP405 Won't Work Long Term: Hair Follicle Damage Due to Abuse of the ISR System

67 upvotes 11 months ago

PP405 may damage hair follicles if used long-term, suggesting cycling might be necessary. Combining it with finasteride could help maintain hair growth.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

484 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community DHT and 5AR respect post, it's importance within the brain

in Research/Science 111 upvotes 2 years ago

The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

community Protein's role in hair growth is more nuanced than just quantity

in Technology 5 upvotes 4 months ago

Protein's role in hair growth is complex, with specific amino acids like cysteine being crucial for effective hair growth. Users discussed using l-cysteine supplements, noting reduced hair loss and faster growth, though some experienced digestive issues.

community protein powder and creatine ????

11 months ago

Minoxidil is being used for hair loss, and there is concern about whether protein powder or creatine affects hair condition. Creatine is debated, with some users reporting no effect on hair loss, while others suggest it may cause hair thinning in those predisposed to alopecia.

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