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research Self-Amplifying RNA Approach for Protein Replacement Therapy

8 citations , October 2022 in “International Journal of Molecular Sciences”

This review explores the potential of self-amplifying RNA technology for protein replacement therapy in various health disorders but reports no new experimental results, indicating challenges remain for clinical approval.

research MON-203 Dermatological Effects Of Hormone Replacement Therapy

October 2025 in “Journal of the Endocrine Society”

This research review observed that topical hormone replacement therapy, particularly estradiol and estradiol-testosterone combinations, significantly increased Type I and III collagen synthesis in the skin of postmenopausal women, suggesting benefits against collagen loss-related skin aging effects such as reduced elasticity and increased dryness.

research High-Dosed Intravenous Iron Replacement Therapy for Iron Deficiency Anemia Does Not Hinder Drug-Induced Amelioration of Disease Activity in IBD Patients

February 2018 in “The American Journal of Gastroenterology”

This study observed that intravenous ferric carboxymaltose did not inhibit the drug-induced reduction of inflammatory activity in patients with inflammatory bowel disease, as indicated by lower CRP levels.

research P730 High-dosed intravenous iron replacement therapy does not hinder drug-induced amelioration of disease activity in IBD patients with iron deficiency anaemia

January 2018 in “Journal of Crohn s and Colitis”

This study found that high-dose intravenous ferric carboxymaltose may reduce inflammatory activity in patients with inflammatory bowel disease and iron deficiency anaemia, as evidenced by decreased CRP levels and improved clinical disease indices.

research Testosterone therapy in men: Clinical and pharmacological perspectives

25 citations , March 2000 in “Journal of Endocrinological Investigation”

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

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community 19 months Topical Min/Fin - 7 months HRT

1072 upvotes 3 months ago

The user experienced significant hair regrowth and fullness after starting hormone replacement therapy (HRT) with sublingual estrogen and spironolactone, in addition to using a topical solution of minoxidil, finasteride, ketoconazole, and biotin. They noted initial shedding phases but emphasized that shedding is a sign of future growth.

community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 1 year ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

community Hair thinning after 40 is destroying my confidence need a hair growth supplement.

in Treatment 17 upvotes 1 month ago

A 47-year-old experiencing hair thinning likely due to perimenopause is advised to consider treatments like minoxidil, finasteride, and supplements such as saw palmetto. Blood tests for iron, thyroid, and vitamin levels are recommended, and options like estrogen replacement therapy and hair growth supplements are discussed.

community Minoxidil 5%/FInasteride 0.1% topical - 4 weeks, am I seeing things or is there progress?

in Progress Pictures 28 upvotes 6 months ago

The user is using topical Minoxidil 5% and Finasteride 0.1% for hair loss and is concerned about potential side effects of oral treatments due to a history of depression and testosterone replacement therapy. Other users suggest that oral Finasteride may be more effective, but results typically take several months to a year to become noticeable.

community IGFBP‐rP1 is a potential therapeutic target in androgenic alopecia

in Research/Science 13 upvotes 1 year ago

IGFBP‐rP1 shows potential for treating androgenic alopecia by influencing hair cycle transitions. Increasing IGF-1 levels may have similar effects to Minoxidil and 5-AR inhibitors in reducing hair loss.

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