28 citations,
December 2015 in “Journal of biological chemistry/The Journal of biological chemistry”
Prostasin has two roles in skin: one for normal skin development without needing activation, and another for proper hair growth that requires activation.
52 citations,
October 2012 in “Journal of Dermatological Science”
The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.
User shared a 1-year update on finasteride, noting thicker hair but mild side effects like reduced libido and mild ED. Considering reducing the dose from 1mg to 0.5mg daily to alleviate side effects.
A person experienced side effects from topical finasteride and is now trying a low dose of oral finasteride (0.1mg) for hair maintenance, alongside topical minoxidil, Fluridil, CosmeRNA, and exosomes. They are also taking resveratrol and nettle leaf to mitigate side effects.
Dutasteride may cause chronic infertility by reducing semen volume and motility, with concerns about irreversible prostate fibrosis. Users consider switching to finasteride or using treatments like minoxidil and microneedling, weighing hair preservation against fertility.