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    GlossaryProstaglandin F2α

    naturally occurring compound involved in muscle contraction and inflammation

    Prostaglandin F2α (PGF2α) is a naturally occurring compound in the body that plays a role in various physiological processes, including the contraction of smooth muscle tissues, regulation of the reproductive system, and modulation of inflammation. In the context of hair, PGF2α analogs have been studied for their potential to promote hair growth and are sometimes used in treatments for conditions like alopecia.

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      learn Cetirizine

      popular antihistamine showing promise for hair loss as an anti-inflammatory and prostaglandin inhibitor

      learn Latanoprost

      glaucoma medication with hair follicle stimulant effects

      learn Minoxidil

      An essential vasodilator with some anti-androgenic effects, has excellent safety record

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      community You will lose hair if your prostaglandins aren't in balance

      in Research/Science  54 upvotes 1 week ago
      Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandin equilibrium for potential hair regrowth.

      community Castor Oil - Yay or Nay?

      in Product  10 upvotes 4 years ago
      The conversation discusses the potential benefits of castor oil for hair thickening, with one user noting it may increase prostaglandin E2 and decrease PGD2. The original poster plans to take 1-2ml orally daily.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 month ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

      in Minoxidil  36 upvotes 1 year ago
      The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

      community Painkillers May Block Minoxidil

      in Research/Science  14 upvotes 1 week ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.