January 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature”
A substance called prostaglandin D2 is found more in bald scalps and it stops hair from growing. Blocking its receptor could potentially treat hair loss.
Prostaglandin balance affects hair loss, particularly in conditions like Lichen Planopilaris, where an imbalance can lead to hair follicle damage. Treatments mentioned include prostaglandin analogs and Pioglitazone HCL, with a focus on maintaining prostaglandinequilibrium for potential hair regrowth.
User discusses Pyrilutamide's effectiveness for hair loss, needing more time for results. Others suggest waiting 6-12 months and ask about side effects.
The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.
The user has been using finasteride for 4 months with positive results, including thicker and darker hair. They are seeking advice on maximizing hair growth without minoxidil, using a routine that includes finasteride, rosemary oil, argan oil, topical melatonin, specialized shampoos, and vitamins.
Microneedling may help regrow hair in dormant bald regions by stimulating stem cell transfer. Users discuss its effectiveness and how collagen might aid in the process.