10 citations,
August 2022 in “International Journal of Molecular Sciences”
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
The treatment for androgenetic alopecia involves using finasteride and minoxidil with intense exercise and cold exposure to boost metabolism and reduce androgenic effects, potentially leading to hair regrowth. This approach may activate biological pathways for improved hair and overall health.
The conversation discusses an ideal diet for promoting hair health, emphasizing biotin, collagen, vitamins C and E, zinc, selenium, anti-inflammatory foods, and blood circulation. It also mentions using finasteride, minoxidil, and dermarolling for hair regrowth.
A user reversed hair loss using 10% sulfur soap, which reduced scalp inflammation and possibly demodex mites. The user did not use finasteride or minoxidil, suggesting inflammation may contribute to hair loss.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.