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research Acute dermal and ocular irritation testing of rice bran supercritical CO2 extract (RB-SCE) and 0.5% RB-SCE essence product

2 citations , March 2015 in “Toxicology and Environmental Health Sciences”

This study found that rice bran supercritical CO₂ extract was classified as a non-irritant for ocular use but a moderate irritant for dermal use in rabbits and guinea pigs.

research Formulation and evaluation of herbal microemulsion for controlling hair loss

10 citations , January 2013 in “International Journal of Research in Pharmaceutical Sciences”

This study found that a microemulsion containing extracts of Hibiscus rosa sinensis and Murraya koenigii was non-irritating and more effective at controlling hair loss than a standard marketed formulation.

research Formulation and Evaluation of Polyherbal Oil

1 citations , August 2021 in “International journal of scientific research in science and technology”

This study evaluated a polyherbal hair oil, containing natural ingredients like Hibiscus and Aloe Vera in a coconut oil base, for its phytochemical properties, antimicrobial activity, and potential to reduce dandruff and hair loss while promoting hair growth.

research Combination of Candlenut (Aleurites mollucana (L.) Wild) Oil and Celery (Apium graveolens) Extract Stimulates Hair Growth: Formulation and Activity Test of Spray Preparation

August 2025 in “Tropical Journal of Natural Product Research”

This study found that aerosols formulated with celery extract and candlenut oil significantly stimulated hair growth in rabbits without causing skin irritation, suggesting their potential as natural and safe alternatives for treating alopecia.

research Drug Repurposing of Voglibose, a Diabetes Medication for Skin Health

4 citations , February 2025 in “Pharmaceuticals”

In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.

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Community Join

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community 2.5 years Minoxidil and HRT, CPA->Lupron +Minox 5%

in Transgender 611 upvotes 1 year ago

The user experienced significant hair regrowth after 2.5 years of using Minoxidil 5% and hormone replacement therapy (HRT) with Lupron, despite initial scalp irritation. Finasteride was ineffective for them.

community Fats on your Head to Stop Hair Loss?

140 upvotes 2 years ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community I am putting my hair loss treatment on hold until my mental health is better.

in Update 21 upvotes 2 years ago

OP is pausing hair loss treatments to focus on mental health due to anxiety and side effects from RU58841. They plan to try topical finasteride and minoxidil after recovering from pneumonia.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

247 upvotes 7 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Warning: Minoxidil usage around pets

in Minoxidil 454 upvotes 1 year ago

Minoxidil is highly toxic to pets, especially cats and dogs, even in small amounts. Many users have switched to oral minoxidil to prevent accidental exposure to their pets.

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