2 citations
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January 2019 in “Methods in molecular biology” This protocol demonstrates that pharmacological inhibition of TGF-β signaling can enhance the proliferative capacity of mouse and human keratinocytes, facilitating their use in skin research and graft preparation.
101 citations
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December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports the successful differentiation of mouse induced pluripotent stem cells into keratinocytes that can regenerate skin and its structures in an in vivo environment.
January 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study explored how T cells interact with hair follicles in primary cicatricial alopecias by using spatial transcriptomics across mice, dogs, and human samples, revealing specific communication pathways and potential drug targets like CFD and S100A8/9 for future therapeutic research.
13 citations
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December 2001 in “Journal of Investigative Dermatology” This study demonstrated that the tracheal xenotransplant procedure is an effective technique for assessing the invasiveness of epidermal keratinocytes and studying factors affecting hair follicle formation.
38 citations
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June 2018 in “Archives of Toxicology” This review suggests that skin may largely protect itself from CYP-generated reactive metabolites due to higher conjugating enzyme activities, while highlighting limitations in modeling human skin metabolism experimentally.