2 citations
,
March 2015 in “Toxicology and Environmental Health Sciences” This study found that rice bran supercritical CO₂ extract was classified as a non-irritant for ocular use but a moderate irritant for dermal use in rabbits and guinea pigs.
May 2023 in “Jurnal farmasi sains dan praktis” In this research on cinnamon and virgin coconut oil hair tonics, F2 and F3 demonstrated stable physical properties and mild irritation potential, while formula 1 remained non-irritating but less stable regarding pH and viscosity.
August 2025 in “Tropical Journal of Natural Product Research” This study found that aerosols formulated with celery extract and candlenut oil significantly stimulated hair growth in rabbits without causing skin irritation, suggesting their potential as natural and safe alternatives for treating alopecia.
January 2026 in “Derecho y cambio social.” This narrative review found that fragrances and isothiazolinone preservatives in deodorants are key contributors to skin sensitization, while magnesium hydroxide shows promise as a less irritating alternative for managing body odor without blocking sweat ducts.
November 2025 in “Journal of Neonatal Surgery” This study developed an herbal hair oil containing plant extracts such as Aloe barbadensis and Nigella sativa, reporting it showed good antioxidant and antimicrobial activity, suggesting potential benefits for hair growth and hair fall prevention.