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GlossaryProtein-Protein Interaction Network (PPI Network)

complex web of interactions between different proteins within cells

A Protein-Protein Interaction Network (PPI Network) is a complex web of interactions between different proteins within a cell. These interactions are crucial for various biological processes, such as cell signaling, metabolism, and structural organization. Understanding PPI Networks helps scientists identify how proteins work together to maintain cellular functions and can provide insights into diseases like alopecia, where these interactions may be disrupted.

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Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms

research Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms

3 citations, May 2023 in “Precision clinical medicine”

Researchers found four genes that could help diagnose severe alopecia areata early.

research Identification of Key Genes in Type 2 Diabetes-Induced Erectile Dysfunction Rats with Stem Cell Therapy Through High-Throughput Sequencing and Bioinformatic Analysis

2 citations, March 2021 in “Andrologia”

Stem cell therapy affects 15 key genes in rats with diabetes-related erectile dysfunction.

research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions

39 citations, December 2018 in “Methods in molecular biology”

The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.

research LncRNA-miRNA-mRNA Regulatory Networks in Skin Aging and Therapeutic Potentials

3 citations, October 2023 in “Frontiers in physiology”

ceRNA networks offer potential treatments for skin aging and wound healing.

research A Machine Learning and Network Framework to Discover New Indications for Small Molecules

8 citations, August 2020 in “PLOS Computational Biology”

A machine learning model called CATNIP can predict new uses for existing drugs, like using antidepressants for Parkinson's disease and a thyroid cancer drug for diabetes.

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community Attention Finasteride / Dutasteride and Your liver

in Finasteride/Dutasteride 371 upvotes 1 month ago

Finasteride may cause elevated liver enzymes, potentially leading to liver issues, though this is rare. Users should monitor liver function and consider topical alternatives if liver sensitivity occurs.

community Front page article at The New York Times (biggest circulation in the world) regarding notable results with oral minoxidil is a pretty big deal

in Minoxidil 2 years ago

This conversation discusses the potential benefits of using oral minoxidil and finasteride to treat hair loss, with some users sharing their own experiences in taking the medications. Others express concerns about the safety of these treatments.

community The link between hair loss and gut health

in Research/Science 59 upvotes 4 years ago

The conversation discusses the potential link between gut health and hair loss, with personal experiences of hair thinning and stomach issues shared. Some individuals found no success with common hair loss treatments like Minoxidil and Finasteride and are exploring the impact of gut health on hair growth.

community 5 months oralfin, topmin, dermarolling

in Progress Pictures 857 upvotes 1 year ago

The user "ninezske" shared their progress pictures of hair regrowth after using oral finasteride, topical minoxidil, and dermarolling. Other users commented on the results and discussed the effectiveness of minoxidil and finasteride.