Activin A promotes ear hair cell development, while follistatin delays it.
Four transcription factors can convert mouse cells into hair cell-like cells, aiding hearing loss research and treatment.
20 citations
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May 2011 in “Journal of Clinical Investigation” The study created a mouse model to mimic degenerative diseases for testing tissue repair and new therapies.
26 citations
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October 2023 in “Neuroscience Bulletin” Stem cell therapy could help regenerate inner ear hair cells to treat hearing loss.
15 citations
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June 2019 in “eLife” Activin A and follistatin control when hair cells develop in mouse ears.