research Controversy: Synthetic hairs and their role in hair restoration?
This article reviews the use of artificial hair fibers, discussing their controversial history and the FDA ban, and reports no new research findings.
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5 / 1000+ resultsresearch Anabolic androgenic steroids and carcinogenicity focusing on Leydig cell: a literature review
This review discusses the potential carcinogenic effects of anabolic androgenic steroids, particularly regarding Leydig cell tumors, and highlights the need for preventive information campaigns due to associated health risks.
research Research on the Mechanism of Hair Dyeing Agents and Strategies for Health Risks Reduction
In this study, researchers explored the potential allergenicity and harmful effects of hair dyes, noting that adverse effects such as sensitization and potential carcinogenicity are not inevitable and can vary based on individual physiological differences.
research Topical L‐thyroxine: The Cinderella among hormones waiting to dance on the floor of dermatological therapy?
This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.
research New intranasal and injectable gene therapy for healthy life extension
This study found that gene therapy using a mouse cytomegalovirus vector with telomerase reverse transcriptase or follistatin significantly extended lifespan and improved health markers in mice, without adverse effects.
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5 / 1000+ resultscommunity Does RU58841 potentially cause cancer?
RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.
community Why don’t more people use hair fibers?
Hair fibers can effectively cover thinning hair when used with minoxidil and hairspray but require daily application and can be inconvenient in certain conditions. Some users prefer treatments like finasteride, dutasteride, microneedling, or wigs due to the maintenance and limitations of hair fibers.
community Potential pp405 info next week at masters of athetics
Discussion on hair loss treatments, focusing on pp405, with skepticism about its effectiveness and concerns about its association with the cosmetic industry. Users also mention treatments like Minoxidil and Finasteride.
community Potential ( but not yet confirmed ) pp405 leak through korean media.
A peptide-based hair loss treatment, PP405, reportedly increased hair density by 62% in 90 days, but these claims are unverified and met with skepticism. Users compared PP405 to Minoxidil and Finasteride, expressing doubts about its effectiveness without more evidence.
community Potential role of TB-500 Thymosin Beta-4
The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, RU58841, and TB-500 Thymosin Beta-4. It critiques the credibility of biohacking claims.
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5 / 33 results- What is SCUBE3 and why is it being studied as a potential breakthrough for hair regrowth? SCUBE3 is a signaling protein that made resting hair follicles start growing in mouse experiments in a 2022 study. It has not been tested in people and is not an approved treatment.
- How does Setipiprant work on the scalp to potentially promote hair regrowth? Setipiprant blocks the DP2 (CRTH2) receptor that prostaglandin D₂ acts through, and PGD₂ is reported to be elevated in balding scalp — but the one published placebo-controlled trial in men (DuBois 2021, n=169) found no significant hair regrowth. It is an experimental compound, not an approved hair-loss medicine.
- Why is valproic acid not considered a standard cosmetic ingredient despite its potential effects on hair growth? Valproic acid is a prescription anticonvulsant with a boxed warning for liver failure, pancreatitis and harm to an unborn baby, so it is regulated as a drug, not a cosmetic. Its hair-growth evidence is mostly cell and mouse work plus one small human trial, and oral valproate itself causes hair loss in some patients.
- What is rapamycin, and how is it being studied as a potential treatment for hair loss? Rapamycin is being studied for hair loss due to its effects on the mTOR pathway.
- What is TDM-105795, and why is it being studied as a potential product for hair loss and hair growth support? TDM-105795 is an experimental topical drug that has been tested only in men with androgenetic alopecia, in two Phase 1 studies and one 16-week Phase 2 trial of 71 men. It is not approved, and no peer-reviewed trial results have been published.
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