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research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior

32 citations, September 2018 in “Journal of pharmaceutical sciences”

The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.

research The Role of Tight Junctions in Skin Barrier Function and Dermal Absorption

156 citations, August 2016 in “Journal of controlled release”

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

research Physical Methods for Topical Skin Drug Delivery: Concepts and Applications

22 citations, November 2018 in “Brazilian Journal of Pharmaceutical Sciences”

New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.

research Kinetics and Equilibrium of Solute Diffusion into Human Hair

8 citations, July 2012 in “Annals of biomedical engineering”

Hair absorbs molecules differently based on their size, charge, and love for water, and less at higher pH; this can help make better hair products.

Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study

research Development of a Two-Dimensional Model for Predicting Transdermal Permeation with the Follicular Pathway: Demonstration with a Caffeine Study

35 citations, June 2017 in “Pharmaceutical research”

Researchers developed a model that shows hair follicles increase skin absorption of caffeine by 20%.

View more "porous pathway" in research →

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community 10 months on dutasteride. Lost about half of my hair density. Losing 150-250 hairsevery day

in Finasteride/Dutasteride 68 upvotes 5 months ago

User experienced significant hair loss after adding dutasteride to their finasteride and minoxidil regimen. They plan to revert to finasteride only due to lack of improvement.

community Topical dutasteride %? And do you apply it every day? Can someone knowledgeable confirm or deny my understanding?

in Finasteride/Dutasteride 5 upvotes 1 year ago

Topical dutasteride used at 0.1%. Dutasteride accumulates in blood, stays for months, and daily use may be stopped after a while.

community Collagen/Vitamins/Supplements and skin-care routine while on Minoxidil?

in Minoxidil 29 upvotes 4 years ago

Minoxidil users discuss skin-care routines to counteract side effects like dark circles and dull skin. Recommendations include vitamin C, potassium, collagen, retinol, nizoral shampoo, and emu oil.

community 2 months back on Fin/Min after stopping treatment for 2 years. First pic is a bit deceptive because I had a 1mm buzzcut and lighting right above me, but it's definitely filling back in.

in Progress Pictures 406 upvotes 6 months ago

A user shared progress pictures showing significant hair regrowth after two months back on finasteride and minoxidil, following a two-year break. The user also mentioned experimenting with hair dye and considering growing their hair for an undercut.

community What size of derma roller is proper for hair regrowth?

in Microneedling 9 upvotes 2 years ago

User has been using Minoxidil twice daily for a year with good results and is considering adding a 1.5mm titanium derma roller for better hair regrowth. They seek advice on the best derma roller size and frequency of use, suggesting once a month or every 3-4 weeks.