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research Cutaneous, Cranial, and Skeletal Defects in Children and Adults with Focal Dermal Hypoplasia

4 citations , October 2023 in “Children”

This study diagnosed a group of six girls with various ectodermal abnormalities, identifying cranio-skeletal malformations consistent with focal dermal hypoplasia (Goltz syndrome), and found heterozygous mutations in the PORCN gene in two children.

research Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies

34 citations , April 2014 in “Psychopharmacology”

This review discusses the pharmacological properties and physiological regulation of neuroactive steroids, focusing on their varied responses to stress and ethanol in rats, mice, and humans, but it reports no new findings.

research Neuroactive Steroids and Ethanol Exposure: Relevance to Ethanol Sensitivity and Alcohol Use Disorders Risk

1 citations , January 2019 in “Elsevier eBooks”

This review suggests that GABAergic neuroactive steroids modulated by alcohol could play a role in vulnerability to alcohol use disorders, providing a rationale for further therapeutic exploration.

research The Genetics of Human Skin Disease

24 citations , October 2014 in “Cold Spring Harbor Perspectives in Medicine”

Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.

research Le gènehairlessde la souris

4 citations , May 2006 in “médecine/sciences”

This study suggests that the hairless gene encodes a nuclear factor important for hair follicle integrity, and its absence leads to hair follicle loss and defects in tissue development.

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community Do you think people of previous generations had better hair? What changed?

2171 upvotes 11 months ago

Hair loss is less common now due to accessible treatments like finasteride, minoxidil, and hair transplants. Improved hair care, skincare, and lifestyle changes contribute to people looking younger today.

community How many guys here experiencing sides from Fin also watch porn regularly?

22 upvotes 2 days ago

Some users attribute erectile dysfunction (ED) to finasteride, but others suggest porn use or other factors might contribute. There are mixed opinions on finasteride's side effects, with some experiencing mental health issues and others defending its use for hair loss.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 year ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community Sexual Sides? Are you sure you don't masturbate too much?

13 upvotes 9 years ago

Finasteride can cause sexual side effects, and reducing porn and masturbation may help improve sexual function. Some users experience persistent issues even after stopping finasteride.

community The meds work: my dad at 23 yo vs me at 35 yo

1791 upvotes 1 year ago

Finasteride and oral minoxidil effectively maintain a youthful appearance and full head of hair, despite genetic predispositions to balding. The discussion also considers the impact of DHT blockers on masculinity and aging, with lifestyle choices like sunscreen use and a vegetarian diet mentioned.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi