research The dermatological consequences of obesity
This review addresses obesity-related dermatoses and highlights the potential increased risk of skin cancer associated with obesity; it presents no new clinical findings.
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5 / 247 results research A Founder Mutation in the POMC 5′-UTR Causes Proopiomelanocortin Deficiency Through Splicing-Mediated Decrease of mRNA
This study identified a novel homozygous mutation in the 5'-UTR of the POMC gene, suggesting a new molecular mechanism for the syndrome of adrenal insufficiency, obesity, and red hair.
research UDP-GlcNAc-1-Phosphotransferase Is a Clinically Important Regulator of Human and Mouse Hair Pigmentation
GNPTAB gene is crucial for normal hair color in humans and mice.
research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.
research Skin transcriptomic and selection signature analyses identify ASIP as a key gene in cattle coat color determination
This study investigated the genetic basis of coat color variation in cattle using skin transcriptome and whole-genome analyses, identifying the ASIP gene as a significant determinant that is differentially expressed and under strong positive selection in black and brown cattle breeds.
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