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This source highlighted the promising potential of polynucleotides in aesthetic medicine but emphasized the need for rigorous, high-quality studies to validate their effectiveness and safety.

This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.

This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.

This review compares DNA-derived biopolymers, PN and PDRN, in dermatology, emphasizing their distinct molecular characteristics and roles, and reports no new clinical results.

This review discusses current findings in regenerative dermatology, noting promising results for therapies using exosomes and polynucleotides in skin rejuvenation and healing, while highlighting the need for more standardized protocols and long-term studies to confirm their effectiveness and safety.