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research Genome-Wide Association Meta-Analysis of Individuals of European Ancestry Identifies New Loci Explaining a Substantial Fraction of Hair Color Variation and Heritability

94 citations, April 2018 in “Nature Genetics”

New genetic locations explain much of hair color variation in Europeans.

research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report

1540 citations, October 2008 in “Fertility and Sterility”

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

research Genetic Basis of Alopecia Areata

40 citations, October 2012 in “Dermatologic clinics”

More research is needed to understand the genetic causes of Alopecia areata to develop better treatments.

research Alopecia Areata Update

49 citations, April 2000 in “Journal of The American Academy of Dermatology”

Despite progress in treatment, the exact cause of Alopecia areata is still unknown.

research Recent Advances in the Genetics of Alopecia Areata

April 2023 in “Medizinische Genetik”

New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.

View more "polygenic nature" in research →

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community UPDATE: The theory that explains everything. Please help me make this big!

in Research/Science 449 upvotes 3 years ago

Hair loss theory involves 3alpha-hydroxysteroid reductase (3AHD) converting DHT to androstenol. Discussion explores potential treatments and encourages more research.

community After 11 Years On Finasteride, Unfortunately, Hair Is Starting To Thin Again. Does Hair Simply Get More Sensitive To DHT As You Age?

in Finasteride/Dutasteride 95 upvotes 6 months ago

After 11 years on Finasteride, a user's hair is thinning again, suggesting hair may become more sensitive to DHT with age. They plan to introduce Dutasteride once a week, as they cannot tolerate Minoxidil.

community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found

in Research/Science 47 upvotes 1 year ago

The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.

community 3α-Hydroxysteroid dehydrogenase community driven study, not anytime soon guys.

in Research/Science 105 upvotes 3 years ago

High cost of studying 3α-Hydroxysteroid dehydrogenase in hair loss led to suggestions of crowdfunding for research. Users discussed using Procyanidin B2/melatonin topical treatment and tracking funds with blockchain.

community The Real Cause Of Androgenetic Alopecia

in Research/Science 667 upvotes 1 month ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

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