42 citations
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February 1996 in “Journal of Investigative Dermatology” This study found that spermidine, a polyamine, plays an essential role in hair growth in sheep follicles, while spermine is not required for normal follicle function.
6 citations
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January 2016 in “Bioorganic & Medicinal Chemistry Letters” This study reported that certain minoxidil conjugates, specifically those with spermine, methylenedianiline, and diaminofluorene, were able to induce differentiation in HL-60 acute myeloid leukemia cells without toxicity at a concentration of 10 μM.
10 citations
,
July 1980 in “British Journal of Dermatology” This study observed that applying polyamines to the skin of hairless mice stimulates thymidine incorporation, suggesting polyamines may play a role in DNA synthesis control in the epidermis.
24 citations
,
June 1999 in “Mechanisms of Development” This study found that ornithine decarboxylase expression is linked to cell proliferation and differentiation in hair follicle development and growth.
1 citations
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January 2009 in “Elsevier eBooks” This review discusses the potential enhanced effectiveness of combining Eflornithine cream with laser or light-based systems for facial hair removal and emphasizes the need for safer and more satisfactory solutions.