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research Toll-Like Receptor 3 Agonist, Polyinosinic-Polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes

9 citations, January 2018 in “Acta dermato-venereologica”

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles

research Double-Stranded RNA Induces Inflammation via the NF-κB Pathway and Inflammasome Activation in the Outer Root Sheath Cells of Hair Follicles

22 citations, March 2017 in “Scientific reports”

Double-stranded RNA causes inflammation in hair follicle cells, which may help understand and treat alopecia areata.

research TLR3 Signaling Modulates Immunomodulatory Property of Human Periodontal Ligament Stem Cells

January 2018

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata

research The Possible Role of PTEN-Induced Kinase 1-Mediated Mitophagy in Regulating Inflammasome Activation in the Pathogenesis of Alopecia Areata

April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology”

Activating mitophagy may help manage a key immune response involved in the hair loss condition alopecia areata.

Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice

research Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice

5 citations, January 2022 in “Molecular Medicine Reports”

Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.

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Community Join

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community Started going bald at 21, I’m 32 Now and Decided to Try a Hair Piece.

in Hair Systems 675 upvotes 3 years ago

A user who has started to go bald and decided to try wearing a hair piece, discussing the experience of doing so and sharing tips for maintenance. The conversation includes discussion about confidence in relation to wearing a wig or hair piece, as well as advice on getting it cut and attached professionally.

community If anyone else feels like they’re too far gone for a hair transplant or can’t tolerate finasteride, I highly recommend trying a hair system! You have nothing to lose and it can change your life. I understand the worries and concerns, as I was very nervous/scared before taking the leap. AMA

in Hair Systems 394 upvotes 1 year ago

The conversation discusses the use of hair systems as a solution for hair loss. Users share their experiences, highlighting the natural look, confidence boost, and maintenance requirements of hair systems, while also addressing concerns about cost, stigma, and potential drawbacks.

community Helicobacter's concocted serum v1

7 upvotes 5 years ago

A custom-made serum based on double-blind studies for AGA, which includes natural ingredients such as rosemary oil, procyanidin B-2, saw palmetto extract, curcuma aeruginosa, pumpkin seed oil and castor oil. The user has updated their recipe to include apple poly procyanidin B-2 4% concentration and other ingredients before topping it off with Pura d'or serum.

community Minox. 2.5 percent, Finasteride 1.25mg, Microneedling 1.5 mm, Ketoconazole shampoo and Biotin. Got better until it didn’t. Should I start dutasteride and Ru?

in What should I do? 87 upvotes 3 years ago

User experiencing hair loss tried Minoxidil, Finasteride, Microneedling, Ketoconazole shampoo, and Biotin. Others suggest continuing current treatment for 1-2 years before considering Dutasteride and RU58841.

community At this point in my life, being bald is not for me. I'm going back on to hair systems...

25 upvotes 4 years ago

28-year-old struggles with aggressive hair loss since 18, used minoxidil with limited success. Tried hair systems but found them expensive, shaved head for job interviews but plans to return to hair systems.

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