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research A syndromic extreme insulin resistance caused by biallelic POC1A mutations in exon 10

7 citations , August 2017 in “European journal of endocrinology”

This study suggests that mutations in exon 10 of the POC1A gene may be linked to a distinct clinical condition characterized by extreme insulin resistance and short stature, differing from SOFT syndrome.

Mitochondrial-Related Genes as Prognostic and Metastatic Markers in Breast Cancer: Insights from Comprehensive Analysis and Clinical Models

research Mitochondrial-related genes as prognostic and metastatic markers in breast cancer: insights from comprehensive analysis and clinical models

12 citations , September 2024 in “Frontiers in Immunology”

This study found that metabolism-related genes significantly impact the prognosis and metastasis in breast cancer, and the development of prediction models may guide personalized therapeutic strategies.

research Lipin 1 Gene Polymorphisms in Polycystic Ovary Syndrome

7 citations , March 2011 in “Hormone and Metabolic Research”

This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.

research Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies

February 2026 in “Frontiers in Pharmacology”

This review suggests a shift toward genetically informed treatments for male pattern hair loss by integrating genetic insights and pharmacogenetic markers into therapeutic decision-making.

research Autosomal Recessive Hypotrichosis with Woolly Hair Caused by a Mutation in the Keratin 25 Gene Expressed in Hair Follicles

50 citations , February 2016 in “Journal of Investigative Dermatology”

A mutation in the KRT25 gene causes a rare hair disorder with thin, woolly hair.

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community So many horror stories about switching from fin to dut

in Finasteride/Dutasteride 58 upvotes 6 months ago

Switching from finasteride to dutasteride can cause initial shedding, but many see long-term hair regrowth and stabilization. Responses vary, with some experiencing fewer side effects and others finding it less effective.

community Combining oral dut with topical finasteride for reduced scalp DHT

in Finasteride/Dutasteride 6 upvotes 10 months ago

The conversation discusses combining oral dutasteride with topical finasteride to further reduce scalp DHT levels for hair regrowth. Users debate the effectiveness and safety of this combination, with some suggesting alternatives like topical antiandrogens such as RU58841, fluridil, and alfatradiol.

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Hair System Specialist
Jane Genesi
Marlton, PA, United States

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Jane Genesi