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Glossary Platelet-Rich Growth Factor

concentration of growth factors from blood platelets promoting tissue repair

Platelet-Rich Growth Factor (PRGF) refers to a concentration of growth factors derived from a patient's own blood platelets. These growth factors are known to promote tissue repair and regeneration, making PRGF a popular treatment in fields like dermatology and orthopedics, including applications for hair restoration and wound healing.

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Research

5 / 1000+ results

research The Growth Factors in Advanced Platelet-Rich Fibrin (A-PRF) Reduce Postoperative Complications after Mandibular Third Molar Odontectomy

23 citations , December 2021 in “International Journal of Environmental Research and Public Health”

This study found that advanced platelet-rich fibrin (A-PRF) reduced postoperative complications like pain, trismus, and edema following mandibular wisdom teeth removal.

A Multi-Donor Ex Vivo Platelet Activation and Growth Factor Release Study Using Electric Pulses With Durations Up to 100 Microseconds

research A Multi-Donor Ex Vivo Platelet Activation and Growth Factor Release Study Using Electric Pulses With Durations Up to 100 Microseconds

5 citations , January 2021 in “IEEE Access”

In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.

Individual Variation in Balance Between Platelet-Secreted Growth Factors Causing Contradictory Effects on Hair Follicle Could Potentially Impact Response to PRP Therapy in Patients With Scalp Hair Loss

research 878 Individual variation in balance between platelet-secreted growth factors causing contradictory effects on hair follicle could potentially impact response to PRP therapy in patients with scalp hair loss

1 citations , April 2018 in “Journal of Investigative Dermatology”

In this study, researchers found that the variability in growth factor expression, particularly TGFβ1, in PRP samples could influence patient responses to hair loss treatment with PRP therapy.

research Comparative efficacy and safety of platelet-rich plasma (PRP), injectable platelet-rich fibrin (i-PRF) and concentrated growth factors (CGF) for female pattern hair loss (FPHL): a prospective multicenter randomized clinical trial

April 2026 in “Journal of Dermatological Treatment”

This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.

Platelet Concentrates In Regenerative Medicine: A Comparative Review Of Platelet-Rich Plasma, Platelet-Rich Fibrin, And Concentrated Growth Factors

research Platelet Concentrates in Regenerative Medicine: A Comparative Review of Platelet-Rich Plasma, Platelet-Rich Fibrin, and Concentrated Growth Factors

March 2026 in “Trends in Sciences”

This review suggests that while platelet-rich plasma has the most robust clinical evidence, platelet-rich fibrin and concentrated growth factors are gaining favor due to their ease of use and absence of additives.

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Learn

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learn Platelet-Rich Plasma

growth factors taken from your blood and injected into your scalp to stimulate hair

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.
How does Platelet help reactivate dormant hair follicles in men and women with thinning hair? Platelet-Rich Plasma reactivates dormant hair follicles by delivering growth factors that stimulate hair growth.
How many Platelet sessions are usually needed before noticeable hair growth begins? Noticeable hair growth typically begins after 2 to 3 PRP sessions.
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learn Epidermal Growth Factor

learn Microneedling

technique to create small wounds in skin to activate collagen production and hair growth

learn Beta Polypeptide

learn Overview

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Community Join

5 / 67 results

community PRP + GFC for hair regrowth?..

2 upvotes 2 years ago

A dermatologist recommended PRP (Platelet Rich Plasma) and GFC (Growth Factor Concentrate) for pattern baldness, but online sources suggest they may not be effective. The user is seeking opinions on these treatments.

community Growth factors, VEGF, And more,possible permanent cure for people with moderate hairloss?

3 upvotes 1 year ago

The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.

community Does anyone else have experience with Patented Growth Factors (PGF) Treatments / experiences with depression on Fin/Min/Dut?

1 upvotes 1 year ago

The user is exploring hair loss treatments, including Patented Growth Factors (PGF) and a serum with Copper Peptide, Ceramides, Amino Acids, and Caffeine, while expressing concerns about the cost and effectiveness of PGF. They are also considering starting finasteride due to doubts about PGF's long-term viability and are seeking experiences from others who have used these treatments alongside antidepressants.

community Hair Loss Factors in Moms: Analyzing Hormonal Changes, Stress, Genetics, and More

4 upvotes 3 years ago

Hair loss in moms can be caused by hormonal changes, stress, genetics, and nutritional deficiencies. Solutions include hair toppers, Minoxidil, PRP therapy, and a healthy diet with supplements.

community new hair out of nowhere 3 weeks post HT! no meds, no vitamins, just growth

142 upvotes 7 months ago

After a hair transplant, the user noticed unexpected new hair growth without using medications or vitamins. Many advised starting treatments like minoxidil and finasteride to maintain the results and prevent future hair loss.

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