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Growth Factor Concentrations in Platelet-Rich Plasma for Androgenetic Alopecia: An Intra-Subject, Randomized, Blinded, Placebo-Controlled, Pilot Study

research Growth factor concentrations in platelet‐rich plasma for androgenetic alopecia: An intra‐subject, randomized, blinded, placebo‐controlled, pilot study

13 citations , January 2020 in “Experimental Dermatology”

This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.

research The measurement of haloperidol and reduced haloperidol in hair as an index of dosage history.

72 citations , February 1990 in “British Journal of Clinical Pharmacology”

This study found that concentrations of haloperidol and its metabolite in human scalp hair significantly correlated with the daily dose and plasma trough levels in patients taking haloperidol.

research Tailored Effects of Plasma-Activated Water on Hair Structure Through Comparative Analysis of Nitrate-Rich and Peroxide-Rich Formulations Across Different Hair Types

August 2025 in “Applied Sciences”

This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.

The Administration of Flumethasone by Three Different Routes, Its Measurement in the Plasma, and Some Effects on Wool Growth in Merino Wethers

research The Administration of Flumethasone, by Three Different Routes, its Measurement in the Plasma and Some Effects on Wool Growth in Merino Wethers

9 citations , December 1978 in “Australian Journal of Biological Sciences”

This study found that flumethasone administration in Merino wethers led to variations in wool shedding and initial reductions in wool growth, with full recovery generally observed within 60 days post-treatment.

research Commentary on: The Effects of Lower vs Higher Cell Number of Platelet-Rich Plasma (PRP) in Hair Density and Diameter in Androgenetic Alopecia (AGA): A Randomized, Double-Blinded, Placebo, Parallel-Group Half-Scalp IRB Study

June 2021 in “Aesthetic Surgery Journal”

This study did not report conclusive results on whether a higher dose of platelets in platelet-rich plasma treatment impacts hair density, emphasizing the need for further evaluation of the trial details.

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community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Napkin math: are we using 100x more topical finasteride than necessary?

in Finasteride/Dutasteride 4 upvotes 4 months ago

Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.

community What Do You Guys Think of This Article That Claims Low Dosage Topical Finastride Has No Effect on Serum DHT

in Research/Science 12 upvotes 1 year ago

Low-dose topical finasteride may reduce scalp DHT with fewer side effects than oral finasteride, though it can still lower blood serum DHT. Users report varying experiences, with some finding topical use effective and side-effect-free, while others note significant DHT suppression.

community Dutasteride just FEELS better than finasteride

in Finasteride/Dutasteride 172 upvotes 1 year ago

Dutasteride is favored over finasteride by some for better hair loss reversal, improved skin, and fewer side effects, though individual responses vary. It may also help with dandruff and eczema but has a slightly higher risk of gynecomastia.

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learn Thymosin Beta 4

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