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research Comparative Effects of Zinc Methionylglycinate and Zinc Sulfate on Hair Coat Characteristics and Zinc Concentration in Plasma, Hair, and Stool of Dogs

4 citations , December 2008 in “The Thai Journal of Veterinary Medicine”

This study found that zinc methionylglycinate supplementation improved haircoat characteristics and zinc absorption in dogs compared to zinc sulfate.

research Plasma β‐Endorphin Concentrations During Natural and Artificially Induced Winter Hair Growth in Mink (Mustela vison)

2 citations , October 1999 in “Annals of the New York Academy of Sciences”

This article discusses plasma β-endorphin concentrations during natural and artificially induced winter hair growth in mink but reports no new clinical findings.

Activation of Platelet-Rich Plasma by Pulse Electric Fields: Voltage, Pulse Width, and Calcium Concentration Can Be Used to Control and Tune the Release of Growth Factors, Serotonin, and Hemoglobin

research Activation of platelet-rich plasma by pulse electric fields: Voltage, pulse width and calcium concentration can be used to control and tune the release of growth factors, serotonin and hemoglobin

3 citations , April 2021 in “PLoS ONE”

The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.

research 316 Role of platelet and growth factor concentration in platelet rich plasma therapeutic response to alopecia

July 2022 in “Journal of Investigative Dermatology”

This study suggests that high platelet concentrations in PRP may not be necessary for hair growth in androgenetic alopecia, and certain growth factors might negatively impact clinical outcomes.

research Decreased selenium intake and low plasma selenium concentrations leading to clinical symptoms in a child with propionic acidaemia

21 citations , June 1991 in “Journal of Inherited Metabolic Disease”

This case report observed that a selenium-deficient diet in a child with propionic acidaemia led to macrocytosis and hair abnormalities, which improved with selenium supplementation.

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community Everyone is ignoring that plasma finasteride levels are 100x lower with topical compared to oral.

in Research/Science 140 upvotes 2 years ago

Topical finasteride results in plasma levels 100 times lower than oral finasteride, potentially reducing systemic side effects. Users report similar efficacy with fewer side effects, suggesting a preference for topical application.

community Napkin math: are we using 100x more topical finasteride than necessary?

in Finasteride/Dutasteride 4 upvotes 4 months ago

Topical finasteride concentrations are likely much higher than necessary for effective follicular DHT suppression, with current standards being 100-1000 times above the theoretical minimum. Lower concentrations (0.001-0.0025%) might still work locally while minimizing systemic exposure.

community Has any data on systemic absorption of pyrilutamide been published?

1 upvotes 4 months ago

Pyrilutamide shows minimal systemic absorption with low plasma levels and no accumulation, suggesting it's unlikely to cause systemic side effects. However, full results are not yet published in scientific journals.

community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

75 upvotes 4 months ago

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

community Fin/Dut and Metabolism Speeds…

in Finasteride/Dutasteride 8 upvotes 2 years ago

A user speculates that a fast metabolism might affect the effectiveness of dutasteride for hair loss. Another user argues that drug response is unrelated to metabolism speed.

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