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A Novel Finasteride 0.25% Topical Solution for Androgenetic Alopecia: Pharmacokinetics and Effects on Plasma Androgen Levels in Healthy Male Volunteers

research A novel finasteride 0.25% topical solution for androgenetic alopecia: pharmacokinetics and effects on plasma androgen levels in healthy male volunteers

50 citations , July 2014 in “International Journal of Clinical Pharmacology and Therapeutics”

This study found that both topical and oral finasteride significantly reduced plasma DHT after one week, with lower finasteride plasma exposure for the topical formulation.

Plasma C19 Steroid Sulfate Levels and Indices of Androgen Bioavailability in Female Pattern Androgenic Alopecia

research PLASMA C19 STEROID SULPHATE LEVELS AND INDICES OF ANDROGEN BIOAVAILABILITY IN FEMALE PATTERN ANDROGENIC ALOPECIA

32 citations , January 1990 in “Clinical Endocrinology”

This study found that women with female pattern androgenic alopecia have significantly higher levels of certain androgens and androgen sulfates compared to normal premenopausal women, suggesting markers for diagnosis and treatment efficacy.

research Plasma Androgens in Children and Adolescents

26 citations , January 1982 in “Hormone Research”

This study found that plasma androgen levels tend to be lower than normal in patients with multiple pituitary hormone deficiencies, particularly those with ACTH deficiencies, and that human growth hormone treatment does not affect adrenal androgen secretion.

research Plasma androgens and the presence and course of depression in a large cohort of men

10 citations , May 2021 in “Psychoneuroendocrinology”

This study suggests that circulating androgens produced by the testes have limited clinical relevance to major depressive disorder in adult men, but certain androgens may be linked to specific MDD symptoms.

research PLASMA UNBOUND AND UNCONJUGATED ANDROGENS IN ORIENTAL MEN

5 citations , January 1976 in “Journal of Endocrinology”

This study compared hormone levels between oriental and Caucasian men, finding that while oriental men share similar plasma testosterone levels, their 17-oxosteroid excretion is lower, which may influence beard growth differences.

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community Microneedling versus Platelet-Rich Plasma

10 upvotes 11 months ago

Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

community Is there any home remedy or alternative to Platelet-rich plasma (PRP) treatment for hair loss?

3 upvotes 1 year ago

The conversation discusses alternatives to Platelet-rich plasma (PRP) for treating androgenic alopecia. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Treatment of Androgenetic Alopecia: Current Guidance and Unmet Needs

3 upvotes 3 years ago

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

community Debunking Androgenetic Theory (Hair Transplants)

in Research/Science 25 upvotes 2 years ago

The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

community Platelet rich plasma treatment

in Treatment 6 upvotes 2 years ago

A 27-year-old male experienced rapid hair loss after dengue fever, which activated a balding gene. The doctor suggested platelet-rich plasma treatment for hair regrowth.

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