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This study found that corticotropin-releasing factor influences cytokine expression related to hair growth in human dermal papilla cells and suggests CRF receptor antagonists could be potential treatments for stress-induced hair loss.

This study demonstrated that α-phellandrene promotes dermal papilla cell proliferation through a cAMP-mediated pathway and upregulates VEGF expression, suggesting its potential use in hair loss prevention.

This study reported that the novel AKT inhibitor CCT128930 demonstrated significant antitumor activity in human cancer cell lines and xenografts, highlighting its potential as an anticancer therapy.

In this study, voglibose, commonly used for diabetes management, was found to reduce melanin synthesis and inhibit melanogenic signaling pathways in B16F10 melanoma cells, suggesting it could be repurposed for treating hyperpigmentation disorders with confirmed topical safety in human tests.

This study found that ginsenoside Rf from Panax ginseng may serve as an effective anti-pigmentation agent by inhibiting the CREB/MITF pathway, reducing melanogenesis in melanocytes and UV-irradiated human skin.