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research Adenohypophysitis Associated with Sebaceous Gland Atrophy in a Dog

11 citations , July 1991 in “Veterinary Pathology”

In this case report, a 9-year-old Samoyed dog with a history of dermatitis showed symptoms compatible with chronic sebaceous adenitis, marked by the absence of sebaceous glands and non-granulomatous skin infiltration.

research Endocrinology, Brain, and Pituitary Gland

2 citations , November 2013 in “Elsevier eBooks”

This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.

research Pathways to inflammation: acne pathophysiology

68 citations , May 2011 in “European Journal of Dermatology”

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

research Effects of natural products on skin inflammation caused by abnormal hormones secreted by the adrenal gland

2 citations , May 2023 in “Frontiers in Pharmacology”

This review article summarizes findings that suggest natural products may help treat skin inflammation related to abnormal hormone secretion by the adrenal gland, as they can inhibit inflammation pathways and promote wound healing.

research Pharmacologic Modulation of Sebaceous Gland Activity: Mechanisms and Clinical Applications

30 citations , April 2007 in “Dermatologic Clinics”

This review discusses the mechanisms by which isotretinoin and hormonal therapy treat acne through their effects on sebaceous glands, reporting no new clinical results.

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community How I recovered from 4+ years of severe balding ages 20-24 by dieting, lifestyle changes and ONLY using topical minoxidil

in Progress Pictures 473 upvotes 1 year ago

A user reversed severe hair loss with dieting, lifestyle changes, and topical minoxidil, highlighting reduced inflammation and body fat. The conversation debates finasteride's effectiveness and the impact of diet and lifestyle on hair health.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

41 upvotes 1 year ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community Does finasteride decrease free testosterone?

in Research/Science 186 upvotes 1 year ago

Finasteride may decrease free testosterone by increasing SHBG, potentially causing side effects like reduced libido and hormonal changes. Some find it effective for hair loss, while others experience negative effects.

community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism

in Research/Science 194 upvotes 1 year ago

Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.

community There’s actually a quite good chance that next year, we might see a new treatment get FDA approval for the first time in nearly three decades.

78 upvotes 1 year ago

Breezula, a potential new hair loss treatment, may receive FDA approval soon, but it is expected to be a weaker alternative to finasteride and minoxidil. Concerns include its twice-daily application and possible side effects like HPA axis suppression.

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