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This review discusses the pilocutaneous syndrome of menopause, associated with skin and hair changes due to estrogen decline, and highlights an unmet need for recognition and targeted treatment.

This review introduces the pilocutaneous syndrome of menopause, a set of skin and hair changes linked to estrogen decline, and discusses its recognition, diagnosis, and management without reporting new clinical results.

This study assessed clinical patterns of skin and mucosal symptoms in postmenopausal women, finding that a significant number experienced conditions like atrophic vaginitis, oral complaints, and hair loss, often without realizing their menopausal link.

In this case study, a 34-year-old woman with a rare presentation of pilomatrixoma involving alopecia and skin hypopigmentation showed no improvement in these symptoms despite a 3-month trial of topical steroid treatment, highlighting a potential association between pilomatrixoma and microinflammation.