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research Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth

10 citations , May 2012 in “PloS one”

This study found that non-pigmented hair follicles have significantly lower expression of nucleotide excision repair genes, which may be associated with reduced melanin production capacity in these follicles.

research An Ayurvedic Approach to Palitya (Premature Greying of Hair)

1 citations , May 2023 in “AYUSHDHARA”

This study explores the Ayurvedic concept of Akala Palitya, or premature greying, noting that its incidence is rising due to modern lifestyle changes and environmental factors, particularly in tropical and developing countries.

research Akala Palitya: An Ayurvedic Review

December 2025 in “International Journal For Multidisciplinary Research”

This study highlights the increasing prevalence of premature graying (Premature Canities) in young adults, linking it to factors such as oxidative stress, genetic predisposition, and environmental pollution, with notable concern in tropical and developing countries.

research An Exploratory Review of Madhuka Taila Prati Marsha Nasya in Akala Palitya - Premature Greying of Hair

December 2025 in “Journal of Ayurveda and Integrated Medical Sciences”

This article discusses the ancient Ayurvedic explanations of premature greying, or Akala Palitya, highlighting how modern lifestyle factors like stress and pollution have increased its prevalence, particularly in urban and developing areas.

research HAIR-ROOT ADAPTATION TO MARASMUS IN ANDEAN INDIAN CHILDREN

32 citations , December 1969 in “The Lancet”

This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.

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Community Join

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community Say goodbye to facial hair development Dutasteride

39 upvotes 1 month ago

A 19-year-old started Dutasteride at 17 to combat aggressive hair thinning, which halted his facial hair development despite having strong beard genetics. He also used oral and topical Minoxidil without success for facial hair, and the discussion highlights the impact of DHT blockers on beard growth.

community Ways to prevent hair from becoming grey or delaying the greying of hairs? (Have You Heard of Catalase!?)

23 upvotes 1 year ago

Catalase is discussed as a potential treatment for delaying or reversing grey hair, but no reliable medicine currently exists. Other mentioned treatments include Imatinib, senolytics like Quercetin and Fisetin, He Shou Wu, Argan oil, and reishi mushroom extract, though their effectiveness varies.

community Over 95% of his face is covered in hair.

in Satire 349 upvotes 1 year ago

A young man with hypertrichosis has over 95% of his face covered in hair, sparking humorous comments about hair loss treatments like minoxidil and dutasteride. Users joke about transplanting his facial hair and discuss the challenges of his condition compared to typical balding.

community Story time! The Great Unbalding (PP405)

230 upvotes 11 months ago

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

community Dht kills hair, but no one says why?

in Finasteride/Dutasteride 40 upvotes 1 year ago

DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.

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Learn

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learn Stem Cell Factor

learn Overview

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Scalp Micropigmentation

What pigments are used in scalp micropigmentation? Providers describe SMP pigments as organic, vegan and formulated for the scalp, but these are supplier and marketing descriptions rather than verified specifications, and clinics contradict each other on colour change and chemical content.
Are the pigments used in scalp micropigmentation safe? Providers describe SMP pigments as safe, medical-grade and made for the scalp, but those are supplier and clinic descriptions rather than regulatory approvals: no colour additive is approved for injection into the skin, and allergic reactions to tattoo pigment are documented.

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Clinics

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