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research Xenobiotic-Metabolizing Enzymes in the Skin of Rat, Mouse, Pig, Guinea Pig, Man, and in Human Skin Models

38 citations, June 2018 in “Archives of Toxicology”

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin

353 citations, July 2015 in “Molecular immunology”

Porcine skin is very similar to human skin, making it a useful model for research.

research Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane

211 citations, June 2012

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

research Transdermal Permeation of Drugs in Various Animal Species

149 citations, September 2017 in “Pharmaceutics”

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

research The Transdermal Inhibition of Melanogenesis by a Cell-Membrane-Permeable Peptide Delivery System Based on Poly-Arginine

36 citations, March 2014 in “Biomaterials”

A new skin-whitening agent using a peptide from wheat is safe and effective at reducing skin pigmentation.

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community Discussion: Keratin Microsphere Results

in Treatment 32 upvotes 8 months ago

Keratin microspheres may offer additional mechanisms to combat hair loss compared to minoxidil. The process to create these microspheres is relatively simple and can be done at home with basic equipment.

community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

in Research/Science 732 upvotes 2 years ago

A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 5 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community 21M with a nasty case of MPB; Heres what's on my radar for the future.

in Research/Science 16 upvotes 2 years ago

Hopeful treatments for hair loss, including Verteporfin, Androgen Receptor Degradation, and SCUBE3. These treatments offer potential solutions to slow or stop the effects of androgens on the scalp.

community Verteporfin day 119 update - donor hair regeneration human trial

in Research/Science 146 upvotes 2 years ago

A human trial of verteporfin, a drug that can inhibit wound healing by scarring and promote regeneration of original tissue and hair follicles to provide an unlimited source for hair transplants; people discussed the potential of this drug and how it could be rolled out in mainstream with more doctors getting on board.

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