15 citations
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January 2022 in “Journal of Oleo Science” This study found that a phytosomal delivery system improved the bioavailability of Cuscuta reflexa extract compared to the plain extract, suggesting enhanced potential for this formulation.
11 citations
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January 2024 in “Indian Journal of Pharmaceutical Sciences” This review summarizes the enhanced absorption and bioavailability of phytosome delivery systems, which combine herbal extracts with phospholipids to improve therapeutic potential, and provides an updated overview of their development, commercial availability, and patented technologies.
2 citations
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November 2021 in “International Journal of Applied Pharmaceutics” This study found that a phytosome lotion made from Mangkokan leaf extract, using a green solvent and microwave-assisted extraction, demonstrated greater hair growth activity than 2% minoxidil, with the 30% phytosome lotion showing the highest efficacy in increasing hair length, weight, and diameter.
December 2024 in “International Journal of Newgen Research in Pharmacy & Healthcare” In this study, Eclipta alba phytosomes were developed to enhance the bioavailability and therapeutic efficacy of its bioactive compounds, showing improved in vitro antioxidant activity and significant in vivo anticancer effects compared to the free extract.
October 2025 in “Asian Journal of Pharmaceutical Research and Development” This study reported that phytosome formulations of citrus flavonoids naringenin and naringin showed significantly increased oral bioavailability and plasma drug concentration in rabbits, suggesting that phytosome technology effectively addresses the pharmacokinetic limitations of these compounds.