In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
December 2024 in “Cell Communication and Signaling”
This study found that subcutaneous adipose tissue-derived extracellular vesicles (AT-EVs) protect skin from photodamage by enhancing fibroblast proliferation and reducing oxidative stress compared to those from adipose-derived stem cells.
18 citations
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May 2014 in “International journal of pharmaceutics”
This study found that UVA and UVB exposure increased hydroquinone and sunscreen absorption in nude mouse skin, with less absorption enhancement observed in more lipophilic sunscreens.
Baldness is difficult to cure because current treatments like finasteride, dutasteride, and minoxidil only prevent hair shedding, and new developments are mostly ineffective. Botox shows potential in aiding skin regeneration and hair growth, but maintenance therapy with treatments like dutasteride and minoxidil may still be necessary.
Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skindamage, so stamps or pens are recommended for safer microneedling.
A 25-year-old male seeks advice on improving crown density after two hair transplants and shares his regimen, which includes derma stamping, minoxidil, dutasteride, pumpkin seed oil, vitamins, and ketoconazole shampoo. Feedback suggests reducing minoxidil dosage, derma stamping frequency, and ketoconazole use to prevent skindamage.
User shared before-and-after photos showing significant hair regrowth after using finasteride 1mg daily, minoxidil 5% twice daily, and Nizoral 2% weekly for almost a year. The user noticed more defined and darkening regrown hairs, indicating a new hairline.
Oral minoxidil may cause dry skin and dark eye bags but doesn't significantly age the skin. Topical minoxidil is toxic to cats, and some users prefer finasteride.